The Chatsworth Settlement has a wide range of sources of income in addition to agricultural rents. Several thousand acres of the estate, mostly around Chatsworth and on the Staveley estate, are farmed in hand. A number of properties may be rented as holiday cottages, including Bess of Hardwick's Hunting Tower in the park. Several quarries produce limestone and other minerals.
The 11th Duke and Duchess did not opt for the "theme park" approach to modernising a country estate, but they did throw off the traditional aristocratic reluctance to participate in commerce. The Chatsworth Farm Shop is a very large enterprise in the UK, employing over a hundred people. A 90-seat restaurant opened at the farm shop in 2005. From 1999 to 2003 there was also a shop in the exclusive London district of Belgravia, but it was not successful and closed down. The Settlement also runs the four shops and the catering operations at Chatsworth, paying a percentage of turnover to the charitable Chatsworth House Trust in lieu of rent. It also runs the Devonshire Arms Hotel and the Devonshire Fell Hotel & Bistro on the Bolton Abbey estate and owns the Cavendish Hotel at Baslow on the edge of Chatsworth Park, which is let to a tenant. The old kitchen garden at Barbrook on the edge of the park is let to the Caravan Club, and a paddock at the southern end of the park where bucks used to be fattened for Chatsworth's table is a tenanted garden centre. In both cases the Settlement receives a percentage of turnover as rent. There is also a line of Chatsworth branded foods, endorsed with the Dowager Duchess's signature, which is available by mail order. The Dowager Duchess has also established Chatsworth Design to exploit intellectual property rights to the Devonshire collections, and a furniture company called Chatsworth Carpenters, but the latter has now been licensed to an American company.